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  1. Prolotherapy: What It Is, Uses & Side Effects - Cleveland Clinic

    Feb 28, 2022 · What is prolotherapy? Prolotherapy is an injection treatment used to relieve pain. Your healthcare provider will inject a small amount of an irritant into your body. Dextrose (sugar) solution …

  2. Prolotherapy: Uses and Side Effects - WebMD

    Sep 12, 2023 · Prolotherapy is a therapy used to treat joint and muscle pain. It is sometimes called regenerative injection therapy or proliferation therapy. Prolotherapy involves injecting a sugar or saline...

  3. Prolotherapy Injections - Mass General Brigham

    Prolotherapy is also known as proliferation therapy or regenerative injection therapy. It is a nonsurgical technique that uses injections of concentrated dextrose solution which stimulates growth factor …

  4. Prolotherapy: Effectiveness, Side Effects, and More - Healthline

    May 28, 2020 · Prolotherapy involves injecting a dextrose or saline solution into an injury site to promote a healing response. It is a form of regenerative therapy or proliferation therapy. There are different...

  5. Prolotherapy Benefits, Uses, Facts & Recommendations - Dr. Axe

    Sep 16, 2025 · Prolotherapy is an injection procedure that helps resolve tiny tears or injuries to connective tissue located throughout the musculoskeletal system (ligaments, tendons, muscle fibers, …

  6. What Is Prolotherapy and Can It Replace Joint Surgery?

    Jul 22, 2025 · Prolotherapy, short for “proliferative therapy,” is a regenerative injection treatment that helps repair weakened or damaged ligaments, tendons, and joints. It involves injecting a natural …

  7. Prolotherapy Research and Treatment Guidelines - Caring Medical

    Prolotherapy works by the same process that the human body naturally uses to stimulate the body’s healing system, a process called inflammation. The technique involves the injection of a proliferant (a …