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  1. IA Alteplase Shows Functional Gains After Thrombectomy

    Oct 30, 2025 · Patients with stroke who receive intra-arterial thrombolysis after thrombectomy are more likely to achieve superior 90-day functional outcomes than those given standard care alone.

  2. Delayed STEMI Care Linked to Reduced Heart Function - Medscape

    Apr 8, 2025 · The risk for reduced left ventricular ejection fraction is higher in patients with STEMI receiving delayed reperfusion than in those receiving timely reperfusion, a study finds.

  3. Intra-arterial Thrombolysis Fails to Improve Stroke Outcomes

    Mar 13, 2025 · Two randomized trials in China find that intra-arterial thrombolysis with urokinase or tenecteplase does not significantly improve functional recovery after successful EVT in …

  4. Top Updates in 2025 ACS Management Guidelines - Medscape

    Jun 30, 2025 · Dr Amal Mattu breaks down the key updates — and lingering pitfalls — in the 2025 ACS guidelines that every acute care clinician should know.

  5. More Data Support Later Thrombolysis for Ischemic Stroke

    Feb 11, 2025 · New research provides further evidence that thrombolysis benefits select patients with acute ischemic stroke up to 24 hours after symptom onset.

  6. New Hope for Better Postthrombectomy With IA Tenecteplase

    Feb 12, 2025 · Administering intra-arterial (IA) tenecteplase (TNK) after successful reperfusion by mechanical thrombectomy is safe and leads to better functional outcomes than standard …

  7. New Thrombolytic Choices: Is One Better? - Medscape

    May 1, 2025 · The approval of a second thrombolytic for ischemic stroke raises the question of whether there are patient characteristics or circumstances that would make one drug a better …

  8. STEMI Equivalents You've Got to Know - Medscape

    Nov 14, 2022 · The ACC formally recognizes decades of evidence supporting immediate reperfusion therapy for patients with MI and these ECG changes.

  9. Thrombectomy Choice in Basilar Stroke May Hinge on Clot Type

    A new trial suggests the optimal approach for basilar artery occlusion stroke may vary depending on whether the blockage stems from embolism or intracranial atherosclerosis.

  10. Tenecteplase Matches Alteplase for Ischemic Stroke Care

    Mar 28, 2025 · Tenecteplase provides comparable safety and effectiveness outcomes for acute ischemic stroke as alteplase, new research suggests.