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  1. Median lethal dose - Wikipedia

    In toxicology, the median lethal dose, LD50 (abbreviation for " lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a given substance. [1]

  2. CCOHS: What is a LD₅₀ and LC₅₀?

    Aug 28, 2025 · The LD 50 is one way to measure the short-term poisoning potential (acute toxicity) of a material. Toxicologists can use many kinds of animals but most often testing is done with rats and mice.

  3. What Is an LD50 and Why Is It Important in Toxicology?

    Aug 21, 2025 · The LD50, or Lethal Dose 50%, is a standard measure in toxicology for the acute toxicity of a substance. This metric provides a quantitative estimate of a material’s short-term poisoning …

  4. Understanding LD50 in Toxicology - numberanalytics.com

    Jun 14, 2025 · LD50, or the median lethal dose, is a crucial concept in toxicology that measures the toxicity of a substance. It is defined as the dose of a substance that is lethal to 50% of the test …

  5. What is LD50?: A Comprehensive Guide to the Lethal Dose

    Dec 3, 2025 · Understand what is LD50 and its crucial role in pharmacology and toxicology. Explore its history, calculation, ethical concerns, and modern alternatives to acute toxicity testing.

  6. 7.7.2 Evaluating Toxicity Data | Environment, Health and Safety

    The LD50 describes the amount of chemical ingested or absorbed by the skin in test animals that causes death in 50% of test animals used during a toxicity test study.

  7. Lethal Dose 50% (LD50): AP® Environmental Science Review

    May 7, 2025 · LD50 refers to the amount of a chemical that is lethal to 50% of a test population within a specified period. In toxicology, this measurement provides a standard way to compare the toxicity of …

  8. LD50 Definition & Meaning - Merriam-Webster

    The meaning of LD50 is the amount of a toxic agent (such as a poison, virus, or radiation) that is sufficient to kill 50 percent of a population of animals usually within a certain time.

  9. LD50 Definition - Microbiology Key Term | Fiveable

    LD50, or Lethal Dose 50, is a measurement used to quantify the toxicity of a substance. It represents the dose of a substance that is expected to cause the death of 50% of a tested population, typically in …

  10. What Is the Lethal Dose 50 (LD50) Test? - Biology Insights

    LD50, or Lethal Dose 50%, represents a standardized measure in toxicology indicating the amount of a substance that is expected to cause death in 50% of a tested population.