In biochemistry and pharmacology, the Hill equation refers to two closely related equations that reflect the binding of ligands to macromolecules, as a function of the ligand concentration.

The Hill plot is a linear graph that visualizes the relationship between ligand binding and concentration, specifically using the Hill equation. The y-axis represents the logarithm of the binding fraction, …

Oct 22, 2014 · The interactive graph provided below allows for a good understanding of the Hill equation, how the reaction velocity changes as a function of the substrate concentration, and how …

Apr 21, 2025 · Generally, numeric readouts such as efficacy (Y-axis measurement) and concentrations (X-axis) will be used to plot a dose-response curve using the Hill equation.

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The Hill plot of actual Hb binding data is curvilinear, and cross the x axis only once. Howver, the ends of the curve (at low and high dioxygen) approach straight lines with slopes of 1 (i.e. n=1).

This interactive Hill equation calculator allows users to simulate and visualize cooperative binding behavior in biochemical systems. It's ideal for students and researchers studying ligand-receptor …

Jun 9, 2025 · It is defined as the slope of the Hill plot, which is a graphical representation of the binding data. The Hill coefficient is denoted by n H nH and is a dimensionless quantity. Archibald Hill …

The document discusses the Hill equation, which was formulated by Archibald Hill in 1910 to describe the sigmoidal oxygen binding curve of hemoglobin. The Hill equation can be used to describe the …

Dec 22, 2020 · The graphs of velocity-vs.-concentration curves for reactions with high Hill coefficients are instead sigmoidal , or s-shaped. There is a lot to unpack here regarding the basis for the Hill …