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  1. Benzodiazepines in the Management of Seizures and Status …

    Abstract Abstract Status epilepticus (SE) is an acute, life-threatening medical condition that requires immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE …

  2. Midazolam Dosage Guide + Max Dose, Adjustments - Drugs.com

    Sep 15, 2025 · Detailed Midazolam dosage information for adults, the elderly and children. Includes dosages for Seizures, Epilepsy, Sedation and more; plus renal, liver and dialysis …

  3. Convulsive status epilepticus in adults: Management - UpToDate

    Jul 3, 2024 · Patients with generalized convulsive seizures that are frequent or separated by a period of significantly impaired consciousness (ie, status epilepticus) or who are medically …

  4. Jan 9, 2015 · ANTI-CONVULSANT THERAPY CONCURRENT MANAGEMENT 1st line (seizures ongoing for 5-10 mins) STATUS EPILEPTICUS Lorazepam 4mg IV (push over 2mins), If szs …

  5. Parenteral Benzodiazepines – Core EM

    Jun 29, 2016 · The RAMPART study (Silbergleit 2011) demonstrated IM midazolam was non-inferior to IV lorazepam (2-4 mg) in the pre-hospital setting. However, in the emergency …

  6. Apr 1, 2025 · Maximum total dose 0.2mg/kg IV/IO (Max 10mg) • Administer Midazolam IV only if IV in place when seizure occurs. • Diastat rectal gel: Preferred in patients who are on the …

  7. Status Epilepticus - EMCrit Project

    Apr 15, 2025 · It may allow for rapid seizure lysis followed by extubation within <24 hours (unlike high-dose midazolam infusions, which can take forever to wear off). If propofol is …

  8. Intramuscular versus Intravenous Therapy for Prehospital Status ...

    Feb 16, 2012 · Conclusions For subjects in status epilepticus, intramuscular midazolam is at least as safe and effective as intravenous lorazepam for prehospital seizure cessation.

  9. essful seizure control is the promptness of initiating antiseizure drugs. Intramuscular delivery of midazolam can be more Respiratory decompensation is more commonly encountered in …

  10. Midazolam (injection route) - Side effects & uses

    Nov 1, 2025 · Midazolam injection is also used to treat status epilepticus, a severe type of seizure where there is more than one seizure within 5 minutes. Midazolam is a benzodiazepine. …