Nov 14, 2025 · LRRK2 (Leucine Rich Repeat Kinase 2) is a Protein Coding gene. Diseases associated with LRRK2 include Parkinson Disease 8, Autosomal Dominant and Parkinson's Disease.

Nov 14, 2025 · This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption …

Nov 14, 2025 · WT1 is a tumor suppressor gene associated with the development of Wilms' Tumor, from which it was named. Mutations in exon 7 and 9 of WT1 have been recurrently identified in acute …

Nov 13, 2025 · This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical …

Nov 13, 2025 · Complete information for ASXL1 gene (Protein Coding), ASXL Transcriptional Regulator 1, including: function, proteins, disorders, pathways, orthologs, and expression.

Nov 14, 2025 · This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment …

Nov 14, 2025 · The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the …

Nov 14, 2025 · Complete information for NMNAT2 gene (Protein Coding), Nicotinamide Nucleotide Adenylyltransferase 2, including: function, proteins, disorders, pathways, orthologs, and expression.

Nov 14, 2025 · This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical …

Nov 14, 2025 · This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell …