Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the insulin -regulated …

Here, we summarized the methods and reagents used to determine the expression levels of Slc2a4 mRNA and GLUT4 protein, and GLUT4 translocation in the skeletal muscle, adipose tissues, heart …

Jul 30, 2025 · Glucose Transporter Type 4 (GLUT4) is a key protein involved in how cells take up glucose. This transporter acts like a gate, controlling glucose entry into specific cells, thereby helping …

Ana B. Ropero GLUT4 is the major insulin-stimulated glucose transporter and the main rate-limiting step in insulin-stimulated glucose uptake in muscle and adipocytes. GLUT4 expression in the skeletal …

Skeletal muscle both stores glucose as glycogen and oxidizes it to produce energy following the transport step. The principal glucose transporter protein that mediates this uptake is GLUT4, which …

GLUT4, or Glucose Transporter Type 4, is a protein that facilitates the transport of glucose into cells, primarily muscle and fat cells, in response to insulin signaling.

Aug 5, 2025 · GLUT4 is stored in specialized compartments, known as GLUT4 storage vesicles (GSVs), which translocate to the plasma membrane in adipocytes, or sarcolemma, and the traverse tubule …

The discovery of the insulin-responsive glucose transporter type 4 (GLUT4) protein in 1988 inspired its molecular cloning in the following year. It also spurred numerous cellular mechanistic studies laying …

GLUT4 controls glucose transport into fat and muscle tissues in response to insulin and also into muscle during exercise. Thus, investigation of regulated GLUT4 trafficking provides a major means by which …

Aug 12, 2023 · Glucose transporter type 4 (GLUT4) is a specialized protein responsible for the transport of glucose across cell membranes. This comprehensive article explores the physiology of GLUT4, its …