In order to repair damage to one of the two paired molecules of DNA, there exist a number of excision repair mechanisms that remove the damaged nucleotide and replace it with an …

At least five major DNA repair pathways—base excision repair (BER), nucleotide excision repair (NER), mismatch repair (MMR), homologous recombination (HR) and non-homologous end …

Dec 15, 2025 · During replication, the cell has proofreading machinery within the DNA polymerase itself. For single-stranded DNA damage, the cell can use excision repair techniques and …

Jul 28, 2025 · Cells possess repair systems that maintain the integrity of this genetic information. These cellular defense mechanisms are continuously active, addressing various forms of …

Mar 17, 2025 · Changes in nuclear and genome organization promote the repair of DNA double-strand breaks and genome stability. Processes that are involved include the modulation of …

Sep 8, 2023 · To overcome the harmful effects of DNA damage, cells have various systems such as DNA repair mechanisms, damage tolerance pathways, cell cycle checkpoints, and cell …

DNA repair, any of several mechanisms by which a cell maintains the integrity of its genetic code. DNA repair ensures the survival of a species by enabling parental DNA to be inherited as …

Cells have developed several repair mechanisms to minimize the number of mutations that persist. Most of the mistakes introduced during DNA replication are promptly corrected by …

Aug 3, 2025 · Cells have evolved an arsenal of DNA repair mechanisms—sophisticated molecular systems that detect, assess, and correct damage with astonishing speed and accuracy. DNA …

These mechanisms of DNA repair can be divided into two general classes: (1) direct reversal of the chemical reaction responsible for DNA damage, and (2) removal of the damaged bases …