San Francisco 49ers head coach Kyle Shanahan revealed Sunday night that the team fears running back Christian McCaffrey ...

A picturesque setting of snow was the perfect backdrop for a Buffalo Bills team that has now won its fifth straight AFC East ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday night, winning 35-10 in Highmark Stadium in Orchard Park, N.Y.

Watch highlights from the Week 13 matchup between the San Francisco 49ers and the Buffalo Bills during the 2024 NFL season.

The Buffalo Bills clinched a fifth straight AFC East title as they swept aside the San Francisco 49ers 35-10 in the snow.

Buffalo's Allen became the first quarterback ever to score touchdowns running, passing and receiving in a single game.

The Buffalo Bills host the San Francisco 49ers on Sunday Night Football in a week 13 clash.The Bills (9-2) are coming off six-straight wins while the Niners (5-6) have lost back-to-back games coming ...

Rodney Harrison, Tony Dungy and Jac Collinsworth unpack the upcoming schedules for the Bills and Chiefs to examine which AFC ...

The San Francisco 49ers can't catch a break.Running back Christian McCaffrey left Sunday's 35-10 loss to the Buffalo Bills in ...

Heavy snowfall and numbing temperatures kept parts of the U.S. in a deep freeze Sunday as the Thanksgiving holiday weekend ...

The 49ers had three fumbles in Sunday night's contest, all three of which were recovered by the Bills. San Francisco's ...

Buffalo claimed the AFC East title for a franchise-record fifth straight season with a 35-10 victory over the San Francisco ...