This valuable study presents an analysis of evolutionary conservation in intrinsically disordered regions, identified as key drivers of phase separation, leveraging a protein language model. The ...

Abstract: Exploring drug-target binding affinity (DTA) is essential for drug discovery ... we propose using the multiscale motif-aware relation graph (MMRG) rather than the SMILES representation to ...

Python script to quickly extract promoter and terminator regions with the NCBI API. Search for the presence of individual pattern or transcription factor responsive elements with manual sequence ...

At the end of March BIM 2.0 start-up Motif, which recently came out of stealth, launched its first product, and it’s perhaps not what you expected it to be, writes Martyn Day Motif V1 is a cloud-based ...

The vote, backed by an overwhelming majority of the Alliance’s 129 members, effectively converts key climate requirements into non-binding “best practice” guidance. The decision follows a year-long ...

(University of Cambridge) The manuscript had actually been hiding in plain sight for quite some years in the collection of the Cambridge University Library, overlooked as a piece of parchment binding ...

Department of Toxicology, School of Medicine and Public Health and Department of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China ...

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This repository contains the code, computing environment description, and software/package versions for the analysis of transcription factor motifs and binding sites in the human genome. The ...