In a study published in Nature, researchers led by Prof. Hu Zheng from the Shenzhen Institutes of Advanced Technology (SIAT) ...
Among the 2028 sporadic CRC samples, the MSI analysis identified MSI-H in 203 patients (10%), MSI-L in 60 patients (3%), and MSS in 1765 patients (87%). IHC identified a loss of MLH1 and/or MSH2 ...
According to statistics, at least 70 per cent of colorectal cancers are sporadic, and 25 per cent are caused by inherited genes. The rest 5 per cent are linked to inherited syndromes like Lynch ...
Background and Aim: The aim of the present study was to evaluate associations between mismatch repair (MMR) status and clinicopathological characteristics and prognosis using immunohistochemistry ...