A study has shown that label-free single-cell Raman spectroscopy can track age-related metabolic defects in mouse oocytes, ...

(a) Fluorescence images showing the chromatin in FGO stained with DAPI. Scale bar, 20 μm. Yellow triangles indicate DAPI-dense heterochromatin foci and the red triangles denote the nucleoli or NLBs.

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...

One characteristic of oocyte development and physiology that has been a mystery for 60 years is the highly present cytoplasmic lattices within the cytoplasm of mammalian oocytes. These were initially ...