Week 13 in the NFL is well underway with four games already under our belts over the Thanksgiving and Black Friday holiday. Now, it's time to heat up the leftovers and gear up for a jam-packed Sunday slate where we have a number of key matchups with major playoff implications.

Before looking at SportsbookWire staff's Week 13 NFL picks, here are the against-the-spread (ATS) and Over/Under (O/U) leaders, according to Teamrankings.com. The Detroit Lions (10-1 straight up) head into their Thanksgiving home game vs.

Aaron Rodgers and the New York Jets have lost seven of their last eight games and now will host the Seattle Seahawks for a cross-conference matchup in Week 13. The Seahawks have won five straight against the Jets and Seattle is a two-point favorite according to the latest Week 13 NFL odds.

One fascinating matchup to watch for is wideout Courtland Sutton against cornerback Denzel Ward. The latter leads football with 17 passes deflected. And Sutton is enjoying his best season since his 2019 Pro Bowl campaign. He’s capable of acrobatic, catch-of-the-year grabs on any drive.

Joining me for 2024 is a six-person panel ranging from FTW editors (Charles Curtis, Mary Clarke) to betting analysts (Prince Grimes) to NFL writers (Robert Zeglinski, Andrew Joseph and Meghan Hall). Here are our Week 13 picks:

NFL Week 13 picks, predictions, win probabilities for Chargers vs Falcons, Steelers vs Bengals, Eagles vs Ravens, 49ers vs Bills, this week's games.

There were mixed results in Week 12 of the NFL season. Half of the writers finished profitable on the week and there was a significant difference between the be

The Indianapolis Colts visit the New England Patriots in NFL Week 13 action, both seeking to reverse recent trends.