PDF for Chemistry from the official Rajasthan Board website. Access chapter-wise details for Chemistry with the link to ...

Unlike structure-based models, which are limited to a small set of resolved protein-ligand complexes, ProtoBind-Diff leverages a larger pool of chemical and biological data, which helps the model ...

The image on the laptop screen shows the 3D structure of a large protein-free RNA complex — one of three unprecedented structures their research collaboration discovered using cryo-EM at SLAC.

The physical interactome of a protein can be altered upon perturbation, modulating cell physiology and contributing to disease. Identifying interactome differences of normal and disease states of ...

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging.

Meet BioEmu-1 from Microsoft Research. This deep learning model can generate thousands of protein structures per hour, unlocking new possibilities for protein scientists and drug discovery and ...

Low-density lipoproteins (LDL)—commonly known as bad cholesterol—have long been on scientists' radar as a major contributor to heart disease. But these microscopic troublemakers have hidden ...

ConspectusProtein higher-order structure (HOS) is key to biological function because the mechanisms of protein machinery are encoded in protein three-dimensional structures. Mass spectrometry ...

However, while many existing models have succeeded in incorporating structural information on target proteins, they have not been able to address important interactions between protein and drug ...

In a comprehensive review published in MedComm – Future Medicine, researchers elucidate the transformative impact of deep learning technologies on protein structure prediction. This review ...