The results showed that knockdown of THBS1 increased cell viability while apoptosis rate and expression of apoptosis-related protein cleaved caspase-3 decreased in PDLCs (Fig. 6B ‒D).

Caspase-3-dependent apoptosis is believed to contribute to the brain injury of ischemic stroke, and a caspase-3 inhibitor has been repeatedly reported to reduce the brain injury of ischemic stroke.

The ratio of cell death by apoptosis (cleaved caspase-3) is represented in Figure 7. In GD18, fetuses of the D mothers showed a lower ratio of cells immunostained for cleaved caspase-3 when compared ...

HOUSTON, Feb. 25, 2025 (GLOBE NEWSWIRE) -- Marker Therapeutics, Inc. (Nasdaq: MRKR), a clinical-stage immuno-oncology company focusing on developing next-generation T cell-based immunotherapies for ...

RNA-sequencing of trophectoderm cells showed activated p53 pathway and apoptosis proportionate to the level of chromosomal imbalance. Immunostaining corroborated that aneuploidy triggers proteotoxic ...

Results— Plaque levels of sTRAIL-R2 and sTRAIL correlated to markers of extrinsic induced apoptosis (caspase-3 and -8). sTRAIL-R2 and sTRAIL protein expression were increased in symptomatic carotid ...

These results indicate that Vpu-induced Caspase 3 activation is essential for HIV-1 Vpu-triggered TDP-43 cleavage and aggregation. In light of the fact that TNFα can induce Caspase 3 activation, we ...

The Apoptosis PCR Array (PAMM-012Z, Qiagen) was used for analysis of gene expression in developing mandibular bone while the Osteogenesis PCR Array (Qiagen, PAMM-024Z) was used for analysis of ...