In a small study, researchers have discovered how a set of genes could cause neurons to die in sporadic ... type of motor neuron, that express the marker THY1. In people with ALS, this was linked ...

Of the 91 patients originally diagnosed with PMA, 20 subsequently developed upper motor neuron signs, which would qualify them as having ALS with lower motor neuron onset. Furthermore, upper motor ...

Approximately 5,000 people in the U.S. develop amyotrophic lateral sclerosis (ALS) each year. On average, they survive for ...

People with ALS – the most common form of motor neuron disease – experience problems with walking, speaking, swallowing and ...

Progressive muscular atrophy (PMA) is clinically characterized solely by signs of lower motor neuron dysfunction, so patients with this condition are commonly excluded from ALS clinical trials.