The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...

One of the main issues plaguing the San Francisco 49ers this year is execution. A lot of players have been playing poorly and ...

Ricky Pearsall Jr., the 49ers first-round draft pick, was shot through the chest on Aug. 31 in a robbery attempt.

San Francisco 49ers coach Kyle Shanahan is sharing an update on Trent Williams and his family after the left tackle's son was ...

The San Francisco 49ers claimed running back Israel Abanikanda off waivers from the New York Jets on Tuesday, one day after ...

San Francisco 49ers offense. Scoring touchdowns in the red zone has been abysmal all season long for them and so has putti ...

Heartbreak has struck the 49ers family again with the news that the newborn son of left tackle Trent Williams died on Nov. 24 ...

The Buffalo Bills are used to hosting high-stakes games in the snow. So, it might not be a surprise that they easily defeated ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The San Francisco 49ers will be without their top two running backs for the remainder of the regular season after the pair of ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

The Detroit Lions won't face Christian McCaffrey in Week 17 this season. The San Francisco 49ers running back injured the PCL ...