The Buffalo Bills dominated the San Francisco 49ers on Sunday night, winning 35-10 in Highmark Stadium in Orchard Park, N.Y.

Buffalo's Allen became the first quarterback ever to score touchdowns running, passing and receiving in a single game.

State and team officials brought all hands on deck to ensure that a massive dose of lake effect snow would not hinder Buffalo’s matchup with the 49ers.

The Buffalo Bills host the San Francisco 49ers on Sunday Night Football in a week 13 clash.The Bills (9-2) are coming off six-straight wins while the Niners (5-6) have lost back-to-back games coming ...

Heavy snowfall and numbing temperatures kept parts of the U.S. in a deep freeze Sunday as the Thanksgiving holiday weekend ...

Buffalo claimed the AFC East title for a franchise-record fifth straight season with a 35-10 victory over the San Francisco ...

Allen's final numbers: 13 of 17 passing for 148 yards and two touchdowns, three rushes for 18 yards and a score, and zero ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

Buffalo Bills outside linebacker Greg Rousseau scoops up a fumble recovery as San Francisco 49ers quarterback Brock Purdy ...

RB Christian McCaffrey suffered a knee injury during Sunday night’s game against the Bills and has since been ruled out. ...

Fantasy football analyst Matt Harmon delivers his thoughts on the major happenings of Week 13's Sunday action.

The Buffalo Bills have secured their fifth straight AFC East title thanks to their Week 13 win over the San Francisco 49ers.