The San Francisco 49ers are extremely banged up going into their Week 13 showdown with the Buffalo Bills. However, they will ...

San Francisco 49ers quarterback Brock Purdy official game status revealed for Week 13 primetime matchup against the Buffalo ...

San Francisco's starting quarterback missed last week's loss to the Packers. Here's the latest on whether he'll play in ...

The 49ers take on the Bills on "Sunday Night Football" in Week 13. Here's the latest on if QB Brock Purdy will be available ...

The San Francisco 49ers are visiting the Buffalo Bills, and they’re getting some December Buffalo weather. The Buffalo team ...

The Buffalo Bills take on the San Francisco 49ers on "Sunday Night Football" in Week 13. Following the Miami Dolphins loss to ...

While the 49ers welcome Brock Purdy back to the starting lineup at snow-covered Highmark Stadium, his immediate backup will ...

The San Francisco 49ers released their list of seven inactive players for Sunday night's game against the Buffalo Bills, ...

The San Francisco 49ers will be missing a number of key starters when they face the Buffalo Bills on Sunday. Amid all the bad injury news, the 49ers did get some good news. Quarterback Brock Purdy, ...

The 49ers are 0-3 ATS in their last three games. The Bills are 5-1 ATS in their last six games with five of those six games ...

A pair of Super Bowl hopefuls from each conference meet up on Sunday, Dec. 1 to close out the NFL schedule for the day with ...

The 49ers' other inactives are defensive linemen Nick Bosa (hip, oblique) and Jordan Elliott (concussion), cornerback ...