While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

The Pittsburgh Steelers and Cleveland Browns had one of the most picturesque games in NFL history last Thursday night when ...

San Francisco 49ers head coach Kyle Shanahan told reporters that star quarterback Brock Purdy will practice with the team ...

The San Francisco 49ers received important Brock Purdy, Trent Williams and Nick Bosa injury updates on Wednesday.

There is a High Risk of Weather Impact (ROWI) for the NFL's Sunday Night Football matchup between the San Francisco 49ers ...

The Bills and 49ers play Sunday, Dec. 1 at 8:20 p.m. at Highmark Stadium in Orchard Park. The game will be broadcast on local NBC affiliates, including WHEC Channel 10 in Rochester. The game will be ...

There was a time when most football fans disliked seeing the Detroit Lions on Thanksgiving. The Lions were often bad and the ...

The San Francisco 49ers' 2024 season has not gone as planned. Sitting at 5-6 and in last place in the NFC West, the team is ...

Buffalo Bills team reporter Maddy Glab joins 1st & 10 to breakdown the 49ers-Bills matchup, discuss what to expect on "SNF" ...

San Francisco 49ers head coach Kyle Shanahan and defensive coordinator Nick Sorensen addressed reporters on Wednesday as the ...

Buffalo Bills defensive tackle (and fashion icon) Jordan Phillips again broke out his fan-favorite winter coat during ...

Quarterback Tua Tagovailoa hopes to continue his hot streak in the cold when he and the Miami Dolphins visit Lambeau Field ...