Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...

Fernando Tatis Jr.'s run-scoring hit leading off the 10th lifted the Padres to a 3-2 victory over the White Sox Friday.

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

ET, Jurickson Profar and the San Diego Padres (88-66) face Andrew Vaughn and the Chicago White Sox (36-118) at PETCO Park.

What to look for from the top San Diego Padres and Chicago White Sox players and how to watch the game as they face off on ...

Oddsmakers have listed player props for Jurickson Profar, Andrew Vaughn and others when the San Diego Padres host the Chicago ...

Preview the Sept. 21 matchup between the San Diego Padres and Chicago White Sox with odds over/under, game spread, betting ...

Fernando Tatis Jr. wins game with double leading off the 10th inning; Joe Musgrove throws six scoreless innings ...

San Diego Padres manager Mike Shildt has defended closer Robert Suarez lately but the question must be asked: Does a likely playoff-bound team with World Series dreams have a serious question to ...

In a thrilling finish at Petco Park, the San Diego Padres pulled off a vital 3-2 victory against the struggling Chicago White ...

The Chicago White Sox trailed by two runs as Sosa batted with a runner on and two outs in the ninth inning against the San Diego Padres at Petco Park. After a ball, Sosa fouled off the next three ...