Targeted rewriting of the epigenome promises to overcome several challenges in direct gene editing in patient therapies.

When GTP on Gα is hydrolyzed, the inactive Gαβγ heterotrimer re-associates for a new cycle of activation by the GPCR (Fig. 1) ...

When Florida hired a relatively unknown basketball coach in Todd Golden, expectations were more neutral than high. His second season has changed perceptions.