The breakdown in protein recycling occurs in all three forms of ALS: hereditary, which is called familial; ALS that is not hereditary, called sporadic; and ALS that targets the brain, ALS/dementia.

head of the Genomic Instability Group at the Spanish National Cancer Research Center (CNIO), provides the first evidence that a possible cause of the hereditary type of ALS –familial ALS– is the ...

However, in about 10% of cases, ALS develops in a person with a family history of the condition. Doctors define these cases as familial ALS, indicating that the genetic mutations may have been ...

Mitochondrial genome mutations may be linked to ALS, per a study, opening the door for new ways to diagnosing and treating ...

There are two types of Lou Gehrigs or ALS, sporadic and familial. Sporadic ALS is the common type and familial ALS is linked to inherited genes. In ALS, neurons that control the muscle movements ...