Nitric oxide synthase (NOS) catalyzes the conversion of l-arginine to nitric oxide (NO) and citrulline 1. The NO released is an important signaling molecule and cytotoxic agent.

Fatty acid synthase (FASN) catalyses the synthesis of fatty acids, and this synthetic pathway is upregulated in many tumours. How might FASN and increased lipogenesis be involved in cancer, and is ...