The Miami Dolphins' Week 16 matchup against the San Francisco 49ers at Hard Rock Stadium is losing luster by the minute. What ...

Heartbreak has struck the San Francisco 49ers family again with the news that the newborn son of left tackle Trent Williams ...

The San Francisco 49ers will be without their top two running backs for the remainder of the regular season after the pair of ...

San Francisco 49ers running back Jordan Mason is going on injured reserve, head coach Kyle Shanahan announced.

The 49ers lost running back Christian McCaffrey for the season with a knee injury. His backup, Jordan Mason, will also be ...

Here's everything you need to know about the 49ers current RB depth chart following injuries to Christian McCaffrey and ...

Christian McCaffrey was having a resurgent game against the Buffalo Bills. He finally looked like the player who was supposed ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

San Francisco 49ers star running back Christian McCaffrey departed Sunday night's snow game against the Buffalo Bills early ...

Four NFL games on Thanksgiving and Black Friday kicked off Week 13 action, and the full schedule continues on Sunday, Dec. 1, ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...