Figure 1: The type III secretion system of Gram-negative bacterial pathogens injects virulence factors into host cells. The second class of TTSS-associated chaperones, which are the subject of this ...

Antibiotics are losing efficacy in treating many bacterial diseases owing to increasing drug resistance. Meanwhile, antibiotic development has lagged; the last new antibiotic class was introduced in ...

One of virulence factors found in the influenza A viruses is hemagglutinin (HA). Researchers at Kanazawa University have recently studied the structure of HA of avian influenza virus, H5N1, using high ...

A team from the Institut National de la Recherche Scientifique (INRS) has made a scientific breakthrough regarding the virulence strategy employed by the Leishmania parasite to infect cells of the ...

Given that antibiotics are losing effectiveness faster than replacements are being found, a chemist suggests we try a new approach. Drugs that hobble the production of virulence factors, small ...

This new information about the origin and genetics of human malaria virulence factors could aid in basic understanding of the causes of malaria and provide targets for drugs and vaccines. "The ...

In a new study, published today in Nature Communications, a multi-center team led by the Wellcome Sanger Institute, the University of Oslo, Imperial College London and UCL, has mapped for the first ...

Chagas' disease affects over 18 million people in Latin America. The agent responsible is a protozoan parasite, Trypanosoma cruzi, transmitted by haematophagous insects. For survival in the host's ...

The PrIMAVeRa project develops a platform to evaluate how mAbs can combat AMR by reducing antibiotic use and providing ...

Scientists from the Institut Pasteur and McMaster University have discovered that the evolution of a gene in the bacterium responsible for bubonic plague, Yersinia pestis, may have prolonged the ...

The influenza A viruses, which have instigated deadly pandemics in the past, still remain a major global public health problem until today. Molecules known as virulence factors are produced by ...