At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

A study finds that, in mouse models, cancer cells from metastatic lymph nodes can escape into the circulation by invading nodal blood vessels, leading to the development of metastases in other ...

Using detailed genetic analysis and manipulation, researchers show that continuous T-bet expression in these cells is key to ...

Leukemia - Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1 Skip to main content Thank you for visiting nature.com.

T-bet is a transcription factor, one of the control proteins in the cell nucleus that can turn specific groups of genes on ...

This didn’t satisfy Masopust, so his team took cells from the immunized mice’s spleens and lymph nodes, expanded the cell populations in test tubes, injected about 100,000 into new mice, and ...

Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis. Science Translational Medicine , 2014; 6 (249): 249ra109 DOI: 10.1126 ...

How, exactly, dendritic cells get from the tissue into lymphatic vessels and from there to the lymph node is the focus of research conducted by Cornelia Halin, professor of pharmaceutical ...

A mouse lymph node from young mouse fourteen days after immunisation. B cell follicles are shown in yellow (IgD) and proliferating germinal centre cells (Blue, Ki67) are shown within the B cell ...

Moreover, the research team adorned the scaffold with two pivotal signaling molecules for T cell activation—anti-CD3 and anti-CD28 antibodies—further emulating the antigen-presenting cells ...