Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

When you buy through links on our articles, Future and its syndication partners may earn a commission. POLG-related diseases are a diverse family of conditions all caused by mutations in a gene for a ...

The mitochondrial genome of Trypanosoma brucei is uniquely organised as a kinetoplast, a highly complex network composed of thousands of minicircles and a smaller number of maxicircles. This structure ...

Tsukuba, Japan—Mitochondria are intracellular organelles that evolved from a bacterium belonging to Alpharoteobacteria, which was taken up as an endosymbiont by the common ancestor of eukaryotes.

Reactive oxygen species (ROS) were long regarded as harmful by-products of mitochondrial metabolism, but growing evidence—including our own—shows that ROS also signal to core processes such as ...

Mitochondria are structures within cells that convert the energy from food into a form that cells can use. Although most DNA is packaged in chromosomes within the nucleus, mitochondria also have a ...

Scientists have found DNA in the nucleus of brain cells, where it shouldn’t be. Bits of genes that typically reside in mitochondria insert themselves at unexpectedly high rates into brain cells’ ...

Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...