This review is the first to provide a comprehensive overview of the latest advancements in metastatic brain tumors. Professor Rongrong Zhou and colleagues not only highlight preclinical progress, such ...

“It really tells us it's not about the genetics [of the tumor],” said Joyce. “It's really about the microenvironment, and the brain microenvironment is profoundly more immune suppressive than in ...

In patients with metastatic breast cancer (BC), the prevalence of brain metastases increased with each treatment line, rising the most among patients with hormone receptor (HR)–negative, human ...

At certain point of cancer progression, primary localized tumors may disseminate to distant organs, including lymph nodes, lungs, bones, liver, or brain. The current options to treat cancer metastases ...

The incidence of breast cancer in women has increased significantly over the past few decades, but advancements in targeted therapies have led to a decrease in death rates. Although systemic ...

Decisions around screening for brain metastases in patients with metastatic breast cancer (MBC) can be challenging. To shed some light on the latest screening guidelines and their implications for ...

Adolescents and young adults with stage IV cancer have unique primary tumor sources and survive longer with synchronous brain metastases than older adults.

To understand what makes breast cancer spread, researchers are looking at where it lives - not just its original home in the breast but its new home where it settles in other organs. What's happening ...