Circular plasmid DNA has traditionally been used as a stable and efficient vector for gene expression and HDR-mediated gene insertion. These vectors typically carry at least one antibiotic-resistant ...

Recently, GenScript made an announcement that demonstrated its commitment to supporting full non-viral cell therapy development into IND-enabling and clinical stages GenScript USA Inc., one of the ...

DNA plays an important role in cell and gene therapies (CGTs), diagnostics, agriculture, and the development of novel technology. To date, CGT research and clinical applications have typically used ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Kano Therapeutics, a biotechnology company pioneering single-stranded DNA (ssDNA) as a safe, efficient and flexible biomolecule for gene insertions, today announced ...

In a study published in Nature Biotechnology on Aug. 28, GAO Caixia's group at the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences and her collaborators at Qi ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

What’s the story behind DNA melting temperature analysis? UV-Visible absorption spectroscopy can be used to assess the characteristics of deoxyribonucleic acid (DNA), a naturally occurring polymer ...

Duplication of DNA genomes requires unwinding of the double-strand (ds) DNA so that each single strand (ss) can be copied by a DNA polymerase. The genomes of eukaryotic cells are unwound by two ...

Spun out of MIT, the company is engineering a new class of biomolecules at 10x lower cost and drastically increased scale to advance gene editing toward cures for complex diseases. “We believe curing ...