University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a "two-in-one" molecule that ...

A groundbreaking review by researchers at Central South University highlights six critical signaling pathways—CCNE1/CDK2, MYC/CDK9, CDK4/CDK6/FOXM1, PTEN/PI3K/AKT/mTOR, AURKB, and VEGFA/VEGFR—as ...

Northwestern Medicine investigators have discovered a new combination approach that may improve the efficacy of MYC inhibitor drugs for treating aggressive and treatment-resistant cancers, according ...

Both MYC amplification and high MYC protein expression have been associated with survival in exploratory studies. 8, 11, 13, 23, 24 The absence of prognostic value of MYC amplification in this study ...

In a landmark study published in Current Molecular Pharmacology, a team led by Dr. Zhen Zhang from Central South University has identified six pivotal ...