Get the opening NFL Week 18 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Jan. 3, 2026.

Antetokounmpo will have the opportunity to play four games in Week 11 against some of the NBA's worst defenses.

NBC and Peacock reload for more NFL action that comes with big playoff stakes on Sunday, December 28, when the Chicago Bears visit the San Francisco 49ers in a Sunday Night Football battle. Kickoff time arrives at 8:20 p.m. ET from Levi’s Stadium in San Francisco, with the game set to broadcast live on NBC and in simulcast on Peacock.

For Week 17 NFL betting, SportsLine AI has evaluated the NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the Week 17 NFL schedule here. After analyzing every game in Week 17, the AI says the Steelers (-3.5, 34), who have won three in a row, cover comfortably against the Browns.