Of 24,414 patients evaluated with an EKG, 5,502, or 23%, had mitral annulus calcification, according to the study. Mitral valve disease was observed in 16% of those patients.

Mitral valve dysfunction increased mortality, regardless of the presence of mitral annulus calcification. But patients with both conditions had the highest mortality, the study finds.

Progression in valvular calcification was 22.3±21.0 percent per year in the atorvastatin group, and 21.7±19.8 percent per year in the placebo group (P=0.93; ratio of post-treatment aortic-valve ...

Non-genetic risk factors for aortic valve calcification include advancing age, high blood pressure, obesity, high cholesterol levels and smoking. Men are at higher risk than women.

Results Valvular Morphology Leaflet calcification was detected in 35, or 87.5 per cent, of the patients. It was marked in 52.5 per cent, moderate in 25 per cent and minimal in 10 per cent.

Patients with mitral annulus calcification are at more than double the risk for mitral valve dysfunction, a study published June 1 in Mayo Clinic Proceedings found. Researchers retrospectively ...

Technical Terms Calcific Aortic Valve Disease (CAVD): A progressive disorder involving thickening, fibrosis and calcification of the aortic valve leaflets resulting in impaired valve function.

Patients older than 18 years with calcific aortic stenosis, defined as an aortic-jet velocity of at least 2.5 m/s and aortic-valve calcification on echocardiography, were included in the study.

The group also identified two SNPs associated with mitral annular calcification, but this finding could not be consistently replicated. The researchers noted that additional studies will be ...

Aortic valve TB Rmax, the study’s primary endpoint, has been used in previous studies because it has the most robust relationship with subsequent calcification, said Kaiser. However, “completely ...

However, it’s possible that the type of aortic valve disease in those analyses—more fibrosis than calcification—differed from the disease of the healthy patients in the Rotterdam Study. Also, ...