The tumor microenvironment (TME) is a critical factor in antitumor immunity and treatment outcome in cancer therapy. We have developed an analysis tool called the immuno-oncology biological research ...

The researchers reproduced cancer cell–matrix interactions in their model by encapsulating cancer tissues within a stomach-derived decellularized extracellular matrix hydrogel. Furthermore, cancer ...

In Singapore, gastric cancer ranks among the top 10 causes of cancer-related deaths and claims about 300 lives each year. Combining state-of-the-art spatial technologies and genetic engineering tools ...

Primary or acquired resistance to immune therapy can arise because of treatment selection pressures that lead to genetic changes in tumor cells; wound healing responses of the microenvironment to ...

Review of spatial biology in oncology today. How whole-tissue imaging of the tumor microenvironment can provide insight into the immune environment of specific cancer types. How AI-driven image ...

The tumor microenvironment (TME) represents a highly complex system that encompasses cellular components (such as cancer cells, stromal cells, and immune cells) and non-cellular components (such as ...

Brain tumors pose significant treatment challenges due to their complex structure and the sensitive location within the brain. Surgical options are often ...

Cancer development and progression is driven by transcriptional, cellular, and spatial changes. Identifying and understanding these changes is essential to better characterizing tumor pathology and ...

Targeted cancer drugs known as CDK4/6 inhibitors have improved outcomes for patients with advanced or metastatic HR+/HER2- breast cancer, but many patients still eventually relapse and become ...

TI-CH remodeled the tumor immune microenvironment and accelerated tumor organoid growth, findings that support a role for an aging-related hematologic clonal proliferation in cancer evolution.

Among the presentations included in the Top Abstracts category at the recently inaugurated Annual Congress of the European Association for Cancer Research (EACR) in Lisbon, it is worth highlighting ...