Transcription factors are a class of proteins that interact with DNA to regulate gene expression. They’re also implicated in many cancers. For years, scientists have considered transcription factors ...

A research team introduces a new large-scale study on human transcription factors combining two state-of-the art interactomics methods that allow rapid identification of protein-protein interactions ...

In Eukarya, RNA Polymerase II (Pol II) transcription is a highly regulated process, which is responsible for the transcription of all protein encoding genes. While the catalytic core of the Pol II ...

DNA, the long polymer curled up inside our cells, is often described as the instructions for life. But those instructions are stored in DNA’s chemical code, and reading that code requires the ...

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human genome, together with protein-coding sequences,” said Donate Weghorn, a ...