Scientists have unveiled part of the protein complex that protects telomeres—the ends of our chromosomes. Telomeres are the protective structures at the end of chromosomes and are essential for the ...

New preclinical study finds boosting NAD+ with nicotinamide riboside alleviated telomere damage, providing protective effect to DNA strands “Telomere attrition is recognized as one of the nine ...

Lausanne, Switzerland, October 4, 2007 – A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, ...

When cells divide, telomeres – the tails of repetitive DNA that extend from the ends of each chromosome – become progressively shorter. Telomeres function like cellular clocks: as they become ...

Lausanne, Switzerland, October 4, 2007 – The group from Prof. Joachim Lingner working at the Swiss Institute for Experimental Cancer Research (ISREC), in collaboration with the University of Pavia ...

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, ...

New findings describe how the enzyme CST is recruited to the end of the telomere, where it maintains telomere length with the help of subtle chemical changes made to the protein POT1. The length of ...

A newly reported case study has documented a novel nonsense variant in the RTEL1 gene in a patient with familial pulmonary fibrosis (PF), adding to an expanding understanding of how telomere-related ...

Leicester, UK - The future risk of coronary heart disease events in middle-aged, high-risk men is correlated with the length of telomeres (the extreme ends of chromosomal DNA that shorten with age) in ...

Telomeres, the protein—DNA complexes at the ends of linear chromosomes, are protected and regulated by the shelterin molecules, the telomerase complex, and other accessory factors, among which is ...