Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

The field of tissue-immune interactions has undergone significant transformation as emerging evidence demonstrates the centrality of local microenvironments ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...

Research teams led by Wolfgang Kastenmüller and Georg Gasteiger have used advanced microscopy techniques to study how T-cells—key players in the immune system—activate and multiply during viral ...

A team identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival. Recent ...