Since the discovery of the double-helical structure of DNA and postulation of the central dogma of molecular biology, stating that the flow of genetic information goes from DNA to RNA to protein, the ...

Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...

Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and ...

This diagram depicts the chemical structure of pyrimidine, a six-membered aromatic ring with two nitrogen atoms at positions 1 and 3 (highlighted in blue). The remaining positions are occupied by ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

In the world of biomolecules such as proteins and the hereditary nucleic acids DNA and RNA, three-dimensional structure determines function. Analysis of the passage of such molecules through nanopores ...