The binding of proteins to DNA is crucial for producing other proteins, ensuring that all the necessary processes in cells ...

Single-cell RNA sequencing has, for over a decade, been unlocking the genetics of single cells and laying the foundations for projects like building cell atlases and uncovering how cells in different ...

Background The rapid advancement of single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened unprecedented ...

More information: Malte D. Luecken et al, Defining and benchmarking open problems in single-cell analysis, Nature Biotechnology (2025). DOI: 10.1038/s41587-025-02694-w ...

BioSkryb Genomics and Tecan Group, today introduced a high-throughput single-cell workflow, combining BioSkryb's 384-well format of the ResolveOME™ Whole Genome and Transcriptome Single-Cell ...

Reconstructing 3D chromosome structures from single-cell Hi-C data with SO (3)-equivariant graph neural networks. NAR Genomics and Bioinformatics, 2025; 7 (1) DOI: 10.1093/nargab/lqaf027 ...

Droplet-based single-cell RNA sequencing of peripheral blood mononuclear cells from 14 JIA patients and four healthy controls (HCs) showed an increase in the levels of monocytes, monocyte-derived ...

Like bacteria, archaea are single-celled organisms. Genetically, however, there are significant differences between the two domains, especially regarding their cell envelopes and metabolic processes.

Single B-cell technologies have emerged as powerful screening tools to accelerate antibody discovery, offering R&D teams the potential to interrogate millions of individual antibody-secreting ...

More information: Verena Körber et al, Detecting and quantifying clonal selection in somatic stem cells, Nature Genetics (2025). DOI: 10.1038/s41588-025-02217-y ...