June 5, 2014 – So-called silent DNA mutations earned their title because, according to the fundamental rules of biology, they should be inconsequential. Reported on June 5 in PLOS Genetics online, ...

Genes hold the recipe for proteins, which are made of amino acids. DNA only has four letters, or nucleotides, and each sequence of three nucleotide bases, or codon, encodes for one amino acid. There ...

Bacteria can acquire resistance to antibiotics through random mutations in their DNA that provide them with an advantage that helps them survive. Finding genetic mutations, and discovering how they ...

DNA has to be interpreted by cells. The letters or bases that make up genetic sequences are read in sets of three, and those three-base sequences are known as codons. Every codon encodes for one amino ...

Researchers led by the University of Bath in collaboration with the University of Birmingham observed the evolution of two strains of the soil bacteria Pseudomonas fluorescens (SBW25 and Pf0-1). When ...

Researchers have identified evolutionary hotspots in DNA where mutations are more likely. The study authors say these findings will help us in the future to predict the evolution of bacteria and ...

A central assumption about so-called synonymous mutations, which are changes in the coding sequence of proteins that do not lead to changes in its amino acid sequence, is being questioned by a study ...

Synonymous or silent mutations do not change the sequence of the protein that they encode. With some exceptions, they do not trigger any effect. Last year, however, a study by researchers from the ...

An optimized version of prime editing technology raises the possibility of a one-time treatment for cystic fibrosis. In their 2019 paper, Liu’s team used prime editing to alter the gene mutations ...

The researchers of this new study wrote that although SMA carrier screening is recommended for all couples, current testing methods primarily focus on copy number loss of SMN1, which can result in ...