DNA replication dynamics in cells from higher eukaryotes follows very complex but highly efficient mechanisms. However, the principles behind initiation of potential replication origins and emergence ...

For all species, the process of DNA replication requires the use of multiple different DNA polymerase enzymes. The primary function of these unique multisubunit enzymes is to ensure optimal DNA ...

From fathers to children, the delivery of hereditary information requires the careful packing of DNA in sperm. But just how nature packages this DNA to prepare offspring isn't clear. Using new ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

Nanoscale “robots” made of DNA that rapidly self-replicate could be harnessed to manufacture drugs or other chemicals inside the body, say researchers. Tiny machines made of DNA origami may make ...