Because the initial decrease in light transmission in platelet aggregometry is attributed to platelet shape change, it is widely held that platelet shape change is a prerequisite for platelet ...

Artificial platelet mimics developed by a research team from Case Western Reserve University and University of California, Santa Barbara, are able to halt bleeding in mouse models 65 percent ...

By mimicking the shape, size, flexibility and surface chemistry of real platelets, artificial platelets are pushed out of the main blood flow to vessel walls. There, the surface chemistry enables them ...

They contain these granules that get released. They change shape when they activate, they can translate and make protein. So I guess it’s kind of a unique thing that they’re made by one type of cell, ...

A research team led by Case Western Reserve University has received a $1.9 million National Institutes of Health grant to develop injectable artificial platelets that halt bleeding by sticking to ...

In 1967 Hardisty and Hutton 7 and Weiss 8 independently described two groups of patients with bleeding disorders in whom a defect in the release of platelet ADP resulted in both impaired release ...

Platelets are clot-forming cell fragments that circulate through the blood. In retrospect, they make perfect sense as the body’s serotonin truckers because they absorb the gut-derived hormone, store ...

Platelets Fuel the Inflammasome Activation of Innate Immune Cells. Cell Reports, 2020; 31 (6): 107615 DOI: 10.1016/j.celrep.2020.107615 ...

Artificial platelets mimics are able to halt bleeding in mouse models 65 percent faster than nature can on its own. They were developed by a research team from Case Western Reserve University and ...