Nucleic acids may be labeled at their 3’ end, 5’ end, or throughout the molecule, depending on the desired application. Myriad of enzymatic or chemical methods are utilized to generate nucleic acids ...

DNA hybridization thermodynamics is critical for accurate design of oligonucleotides for biotechnology and nanotechnology applications, but parameters currently in use are inaccurately extrapolated ...

Multiplexed and quantitative analysis of nucleic acid sequences in complex mixtures is essential in various applications of microbiological research. We have developed a method based on solution ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 77, No. 11, [Part 2: Biological Sciences] (Nov., 1980), pp. 6851-6855 (5 pages) A simple nucleic acid ...

Scientists have invented and developed a powerful nanomaterial that could revolutionize biomedicine: spherical nucleic acids (SNAs). The novel arrangement of nucleic acids imparts interesting chemical ...

Dionex announces the release of two applications notebooks in PDF format: the Protein and Antibody Therapeutics Applications Notebook and the Nucleic Acid Therapeutics. The Protein and Anbtibody ...

(Nanowerk Spotlight) Epigenetic mechanisms are chemical changes in DNA that do not alter the actual genetic code but can influence the expression of genes, and can be passed on when cells reproduce.