With only a few weeks left on the college football slate, NFL draft season is beginning to hit its stride. Before the San Francisco 49ers meet the Buffalo Bills in Week 13, USA TODAY’s NFL Draft Wire released their latest predictions for the 2025 draft with a new mock draft.

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth Lombardi Trophy. The Niners have made four NFC Championship Game appearances in the past five years.

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's game, and Fred Warner has a lingering ankle issue.

The San Francisco 49ers are 5-6 entering their matchup with the Buffalo Bills on Sunday, and an NFL executive called out 49ers HC Kyle Shanahan for mishandling late-game situations. Colin Cowherd discusses this criticism and if it’s the biggest issue the 49ers have right now.

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the 49ers haven't looked good over their last three contests.  It wasn't a surprise the 49ers fell to the Green Bay Packers on Sunday with so many key contributors out.

San Francisco 49ers star linebacker Fred Warner revealed Wednesday that he has been playing through a broken bone in his ankle since September.

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco 49ers and Buffalo Bills.

The Buffalo Bills are in great shape heading down the stretch of this 2024 NFL regular season. Coming out of their much-needed bye week, which, of course, was

During a segment of "Good Morning Football", NFL Network's Peter Schrager coins the last Thanksgiving matchup of the day between the Miami Dolphins and Green Bay Packers as a battle between "two brilliant minds".

NFL Network Insider Ian Rapoport provides the most recent details on several players who are on the injury report of the Thanksgiving Day matchup between the New York Giants and Dallas Cowboys.