San Francisco 49ers wide receiver Deebo Samuel has had quite a turbulent season, and he’s starting to feel the heat because of it. But recently there’s a small yet growing part of the 49ers fan base (and some NFL fans) that is questioning whether or ...

With only a few weeks left on the college football slate, NFL draft season is beginning to hit its stride. Before the San Francisco 49ers meet the Buffalo Bills in Week 13, USA TODAY’s NFL Draft Wire released their latest predictions for the 2025 draft with a new mock draft.

The San Francisco 49ers are 5-6 entering their matchup with the Buffalo Bills on Sunday, and an NFL executive called out 49ers HC Kyle Shanahan for mishandling late-game situations. Colin Cowherd discusses this criticism and if it’s the biggest issue the 49ers have right now.

What to expect from Sunday Night Football's 49ers vs. Bills matchup. This is one of those games that feels like Buffalo's to lose. The Bills are 9-2, sitting at the top of the AFC

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the 49ers haven't looked good over their last three contests.  It wasn't a surprise the 49ers fell to the Green Bay Packers on Sunday with so many key contributors out.

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The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The Bills (9-2) are looking to build on a six-game win streak, while the 49ers (5-6) have lost their last two.

It’s Week 13 in the NFL, and the Buffalo Bills are preparing to host the San Francisco 49ers on Sunday Night Football at 8:20 p.m. Buffalo (9-2) enters the contest having won six straight and is coming off a bye week. Meanwhile, San Francisco (5-6) has dropped two straight and three of five as injuries continue to pile up.

Christen Harper Goff, Alix Earle, Sarah Jane Ramos and more NFL WAGs share with PEOPLE exclusively how they creatively plan to enjoy Thanksgiving on game day

Jordan Love will be front and center against the Dolphins at Lambeau Field on Thanksgiving Day. The Packers QB will excel with the home-field advantage, protecting the ball effectively against an injured Miami secondary.