Week 2 of the 2024 NFL preseason was used as something close to a regular-season dress rehearsal for some teams, while others opted to keep their starters mostly out of harm's way.

Discover the latest Detroit Lions Week 1 odds, betting lines and expert picks for the 2025 NFL season opener. Lions vs. Packers features two Super Bowl hopefuls.

Let's check out the lines for each Monday Night Football game at DraftKings Sportsbook as of July 2. (All times ET) 2025-26 Monday Night Football odds WEEK 1, SEPT. 8 ...