Figure 2. (A) Absorption NIR spectra of API, polymer, and a 50/50 (w/w) extrudate in full scale. (B) Transflectance NIR spectra in common scale acquired during extrusion.

Recent work by a team of researchers at Queen’s University Belfast and University College London has reported on a newly developed strategy for the manufacture of a high drug loaded amorphous solid ...

Nowadays, melt flow index (MFI), also known as melt index (MI) or melt flow rate (MFR), is extensively used to quantify polymer flow behavior. MFI is a measurement of the ease at which a molten ...

Figure 1: Representative schematic of melt-extrusion processing as a function of pressure. (FIGURE 1 IS COURTESY OF THE AUTHOR) Polymer combinations have been shown in numerous studies to yield ...

Formulating drugs for hot-melt extrusion (HME) was one of the topics at the Pharmaceutical Extrusion Seminar organized by Leistritz near the company’s US headquarters in New Jersey in June. Several of ...

Die swell has been used in the plastics industry as a qualitative measure of polymer melt elasticity for quality control. It can also be used in an extrusion process for analysis of extrudate ...

K. Paulsen, A. Gryczke, D. Leister, Investigating process parameter mechanism for succesful scale- up of a hot-melt extrusion process, AppNote LR-71, Thermo Fisher Scientific, 2013.

The Italian company FIMIC has introduced the self-cleaning double-screen melt filter, ERA, which is designed to provide fine filtration for highly contaminated recycled plastic particularly in blown ...