Cellular senescence—an irreversible cell-cycle arrest coupled with the production of pro-inflammatory secretions known as ...

People with lumbar degenerative disc disease will experience constant low back pain that is moderate to severe in intensity. They will describe having focal lower back tenderness that can radiate ...

At least 80% of the adult population is suffering from lower back pain, and 40% of these cases originate in intervertebral disc degeneration.

As populations worldwide continue to age, chronic back pain caused by intervertebral disc degeneration is emerging as a widespread and costly health burden. Now, researchers have uncovered a key ...

Arthritis & Rheumatism. 2006;54(12):3859-3867. Degenerative disc disease is one of today's most common and costly medical conditions. Marked by the gradual erosion of cartilage between the ...

Contacts Orthofix International N.V. Investor Relations Mark Quick, 214-937-2924 [email protected] or Media Relations Denise Landry, 214-937-2529 [email protected] ...

Study Summary Intervertebral disk tissue was obtained from 35 patients undergoing surgery for chronic degenerative disease (n = 25) or an acutely herniated disk (n = 12). Of note, 48% of patients ...

Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-25453-2 ...

Medical device player Orthofix hopes that a new preclinical study of its pulsed electromagnetic field therapy could point to a minimally invasive treatment for intervertebral disc degeneration ...