The innate immune response constitutes the body’s first line of defence against pathogens, utilising a network of pattern recognition receptors (PRRs) and signalling molecules to detect and neutralise ...

When pathogens attack the body, the innate immune system goes to work protecting against the invading disease. The innate immune system is the first line of defense. It detects precisely what the ...

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterised by the production of autoantibodies and the formation of immune complexes, leading to inflammation and multi-organ ...

Milestone marks the third major acquisition for an IFM Therapeutics subsidiary in the past seven years The acquisition provides Novartis with full rights to IFM Due's portfolio of STING antagonists, ...

Sepsis remains a leading cause of morbidity and mortality in critically ill patients, posing a major challenge to modern ...

Researchers at the University of Kansas have discovered a human gene, the protein PARP14, plays a role in regulating interferon, part of the body's innate immune system. Their study, appearing in the ...

This is a preview. Log in through your library . Abstract Type I interferons (IFNs) are innate immune cytokines required to establish cellular host defense. Precise control of IFN gene expression is ...

Researchers at The Jackson Laboratory have created a panel of genetically diverse mice that accurately model the highly variable human response to SARS-CoV-2 infection. Together with collaborators at ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways - ways that have important implications for the development of ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways -- ways that have important implications for the development of ...

When the first cells appeared on Earth approximately 3.8 billion years ago, viruses were already here to greet them. 1 Ever since, viruses have been devising ways to infect cells, and cells have been ...