An MPGN pattern in association with autoimmune diseases often includes multiple immunoglobulins and complement proteins — IgG, IgM, IgA, C1q, C3, and kappa and lambda light chains.

Serum complement levels were decreased in these patients. 10 In a similar group of patients, 11 deposits of immunoglobulin and complement were found in vascular lesions, and in a renal lesion ...

A collaborative team from the Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of ...

A research team has uncovered how glycan modifications dynamically regulate the structure and function of human ...

A multi-institutional team led by the Chinese Academy of Sciences has constructed a proteomic atlas of human aging across 13 organs, revealing tissue-specific aging clocks, transcriptome-proteome ...

These images show whether the deposits in the glomeruli contain immunoglobulin, complement protein, or both. The makeup of the deposits is critical in the diagnosis of either C3G or IC-MPGN.

Mónica Marcela Castiblanco-Valencia, Tatiana Rodrigues Fraga, Ludmila Bezerra da Silva, Denize Monaris, Patrícia Antônia Estima Abreu, Stefanie Strobel, Mihály Józsi, Lourdes Isaac, Angela Silva ...

Lancet. 1985;2 (8453):464-468. Orange JS. Immunoglobulin therapy: standardizing approaches and best practices in rare diseases in the managed care setting. J Manag Care Med. 2011;14 (2):26-33 ...

Most strikingly, IgG deposition was seen on the basolateral epithelial surface in 23/25 autistic children, co-localising with complement C1q. This was not seen in the other conditions.

(A) Measurements of complement components C4, C3 and TCC in convalescent EDTA plasma. Groups divided according to levels of total IgG; high, intermediate, low and negative healthy controls, n = 240.